As some of the team head to France to help aid efforts at a refugee camp, their experiences leave lasting impressions. At the ED, Connie's world is rocked by sudden news.
Conditions at the refugee camp cause a member of the ED team to take drastic action. In Holby, recent events are taking their toll on Jez.
With the findings of the coroner's report due, Ethan struggles to put the past behind him. Iain pretends to be a doctor to impress Lily's family when he attends her cousin's wedding as her date, and Dylan's moral compass gets him in a tight spot.
Dylan's plan to reunite Sanosi with his uncle doesn't turn out the way he would have hoped. Also, Alicia begins her driving lessons with Elle giving her a crash course.
A familiar face returns under a different guise, while Elle questions how happy she is being a single mother.
Connie undergoes tests and, as she anxiously awaits the results, she focuses on Ethan's consultancy revision. Elsewhere, Elle meets a potential love interest.
Connie struggles to deal with the results of her scans and what it means for her future, and Dylan is forced to bring Sanosi into the ED.
Connie's denial about her condition reaches crisis point and she forces Ethan to help her, and Alicia's driving test approaches at speed.
Dylan's secret starts to unravel around him as more people get drawn in, while Lily's jealousy of Sam threatens her budding relationship with Iain.
A near miss with the discovery of Sanosi leaves Dylan at breaking point. David desperately tries to stop his friend making a terrible mistake.
Lily has decided to go for the Research post in Hong Kong with Mr Grayling. Meanwhile, after her run in with Sam, Lily and Iain are on the rocks. Lily is sure that this means she should put herself first. However, when she is called out to help at an RTC there is a moment between them that remind...
Ethan is rocked when he discovers a sinister note in his locker. Fearing the worst, he immediately goes to Connie. Finding it increasingly difficult to keep her illness secret, Connie is rude to Ethan.
A flashback to the secret story of Dylan and his surprise journey with Robyn's ex-fiance, Glen.
Ethan takes Connie for her first day of chemotherapy. Not wanting to show nerves or weakness, she bats Ethan away by putting him in charge of the ED. To Robyn's horror, Glen gets a job as a porter in the ED.
Connie's illness starts to noticeably affect her work, but she continues to brush away Charlie's support. Max, growing tired of his lack of love life, is given hope when attractive new coffee shop worker Polly catches his eye.
Elle has a shock in store for Jacob, while Rash questions his future as a doctor after treating an old girlfriend.
Chemo is taking its toll on Connie, but she is ready to fly to America for Christmas. Sally Hodge is in Holby awaiting results of her biopsy, and the shared house is ready but Glen spots that Robyn is being weirder than usual about moving back in.
Connie takes matters into her own hands while Dylan struggles to keep things together in the ED.
Max is confronted with his estranged wife Zoe, whilst he sees in an old friend what he could have had. Meanwhile, Jacob needs to step up after his son Blake arrives in the emergency department with an injury.
Elle's son turns up in the ED with his injured friend after going missing all night, schoolteacher Justine faces the consequences of her decision, and Ethan goes for his interview.
Dylan's alcoholism spirals out of control whilst he deals with a stabbing victim and her young son, Connie befriends cancer patient Maggie, and Ethan is now in charge of the ED.
Alicia takes matters into her own hands when queuing ambulances put patients in danger, and with the ED in meltdown, Ethan asks Alicia to induct new F1 Bea, who is keen to get going but finds herself shut out of the `excitement' in resus.
On the day of her son's trial, Elle finds herself looking after the boy he assaulted. Are his new injuries related? Meanwhile, Bea's one-night stand leads to her finding out Rash's secret.
Under pressure, Ethan makes a decision that exposes the weaknesses of the ED and gives ammunition to the anonymous blogger. Meanwhile, Gem has her first day as a porter in ED. Iain is nervous for her, but Gem is determined to do well.
Ethan is flying high after kissing Alicia, and a fight between a family gets out of control causing injury to a pregnant mother. Meanwhile, Glen, miserable that his daughter doesn't have the same last name as him, decides to propose to Robyn.
Dylan struggles to keep his alcoholism a secret from his colleagues, and Bea pushes herself to greater heights to impress Ethan.
Pressure on Ethan intensifies as he is given just one day to track down the blog author, Donna helps her bullying sister Kacey with her gymnastic training, and Ethan acts against Charlie's advice and puts Rash in resus, where he must face his fear.
Rash's new found confidence is tested by a prisoner who also leads Gem into danger. Bea treats a veteran who served in the Falklands and goes up against confident F1 Eddie for a coveted training course.
Tragedy strikes on the day of Robyn and Glen's wedding and Jacob feels ignored by Elle. Meanwhile, Rash treats a woman who has suffered from anxiety since losing her fiancé and Alicia and Louise see to a young woman who has suffered a fall.
Glen faces a heart-breaking decision on what should have been the happiest day of his life. Meanwhile, concerned that his alcoholism may be affecting his judgement, Bea asks to shadow Dylan as they treat a young woman who is suffering chest pain.
It's Nicky's ex's wedding and she is despondent and scathing to her friend Abigail, not helped by the first dance being to a song that she though twas special to her and the groom and Leigh-Anne is having a bad day when she is chucked out of her home by debt collectors. Meanwhile, Ethan's pregnan...
Bea's day goes from bad to worse professionally and privately but will it end sourly? Meanwhile, a guilty Ethan offers to help Leigh-Anne financially, but she is suspicious when he promises he wants nothing in return.
Robyn questions whether she is fit to be in work and Ethan is in danger of crossing a line with Leigh-Anne. Meanwhile, Johnny worries about his reputation and a frustrated Bea must make a heartbreaking decision.
Connie is back and she has a big idea for the emergency department, but Charlie's not convinced. Meanwhile, Alicia has got the keys for her new house and the gang convince her to have a house warming and Ethan pays his respects at the spot where his brother died.
Iain and Sam, neck-deep in water and running out of time, are forced to make a life-changing decision. When Bea's secrets are revealed, she finally has to confront her demons, and Duffy is concerned by Charlie's long hours.
Connie unravels a shocking mystery about her friend Maggie, which makes her question her own health. Meanwhile, Bea struggles to find her confidence on her first day back, so Ethan devises a competition to help get her back in the swing of things.
Alicia tries to process the events of her night with Eddie.
Eddie realises that Alicia is frightened of him, and Bea receives a concerning phone call. Meanwhile, Sam and Jacob discuss which of the emergency department staff she would be able to beat, and they decide to do some sparring.
With Dylan AWOL, Connie and Elle are forced to go on a road trip to pitch for funding for a new trauma theatre. Meanwhile, Bea starts to become concerned for Alicia, and Sam flirts with Jacob, teasing him about his accident during their boxing match.
Alicia finally reaches breaking point, only for Ethan to make a shocking confession.
A first day from hell pushes new paramedic Ruby to her limits and beyond. Meanwhile, Alicia struggles to work with Eddie, and Bea forces her to face a crippling truth. Also, Sam apologises to Jacob for standing him up.
Bea tries to help Alicia, but will she be able to face up to what happened with Eddie? Meanwhile, Ruby tries to build bridges with both her teammates and patients, and a father and son are brought to the emergency department with mysterious injuries.
Alicia decides that she wants to put the night with Eddie behind her, and Bea is supportive, but finds it difficult. Meanwhile, a melancholy Luke is about to say goodbye to his girlfriend Daniella, who is joining the army, when she falls ill.
Alicia decides to report Eddie to the police, and he is arrested. Bea is pleased when Alicia informs her that she reported him, and Alicia tells Bea she is not to let her support for her get in the way of her opportunity in Paris.