Daimon Helstrom investigates a possessed young boy in Oregon; Ana Helstrom stages an auction in San Francisco to expose a criminal; disturbing events at St. Teresa's cause concern as the siblings estranged Mother remains hospitalized.
Daimon and Gabriella fight to save a man's soul, while a darker force attempts to stop them. Yen's relationship with his work takes a dark turn towards obsession, and a discovery leads Ana back to St. Teresa's.
Daimon and Ana learn more about the destruction their father left in his wake; with Gabriella, they pay a visit to a potential victim and find themselves in deeper than they ever imagined; Hastings shocks Caretaker with a stunning revelation.
A demonic enemy brings together an unusual group; Daimon and Ana travel to San Francisco in search of Yen and an artifact that may help defeat the enemy.
Things are not what they seem as Mother's health sharply declines; as Ana searches for Yen, Gabriella offers counsel to a student.
A dark force creates a melee forcing Hastings and Ana to work together; Daimon and Gabriella discover the events of the Blood Hotel are connected.
With a powerful demon looking for a new host and Ana struggling to control her darker urges, Daimon is offered a proposition from The Blood.
Relationships deepen as stakes increase; to save a life, Hastings and Ana must do the unthinkable; Gabriella and Daimon journey to his childhood home.
Daimon and Gabriella find themselves in disturbing new territory; Ana has to make a decision that will change the course of the siblings' lives.
Ana and Daimon fight to save a soul, but only Yen can be victorious; Gabriella's newfound perspective challenges Daimon's beliefs, creating rifts in the group.